Motivation
Motivation
Motivation is designed to optimize dopamine signaling and support neurotransmitter balance—the critical processes that keep the brain energized and heighten awareness.
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About this item
- IGNITE ENERGY AND DRIVE: Thesis Motivation is a memory and focus supplement that helps you start tasks with greater focus and determination. It supports mental energy and clarity so you can approach your to-do list with confidence.
- FUEL YOUR MOTIVATION: Our nootropic supplement helps strengthen follow-through by supporting focus, willpower, and motivation. It encourages steady progress and keeps you on task so you can build momentum and complete your goals with confidence.
- TARGETED INGREDIENT BLEND: With Methylliberine, Artichoke Extract, L-Phenylalanine, and L-Theanine, this formula supports brain energy, focus, and self-discipline. Includes an optional caffeine capsule for a personalized experience.
- EASY DAILY ROUTINE: Take one packet daily for 6 days, then rest on the 7th day. Each kit provides a 24-day supply of nootropic brain support supplements that are designed to support focus, motivation & productivity to help build consistent habits.
- UNDERSTANDING NOOTROPICS: Nootropics are naturally derived compounds that support neurotransmitters associated with attention, energy, and mood. Thesis helps personalize your supplement routine based on your cognitive preferences.
Ingredients
• Purine alkaloid (Methylliberine), 100mg
• Theacrine, 100mg
• N-Acetyl-L-Tyrosine (NALT), 400mg
• Rhodiola Rosea (Fermented Salidrosides), 60mg
• Pyridoxal-5’-Phsophate (Vitamin B6), 5mg
• Methylcobalamin (Vitamin B12), 1000mcg
• Camellia siensis (L-Theanine), 200mg
• Caffeine Anhydrous, 150mg
How To Use
Suggested Use: As a dietary supplement, start with 1 capsule in the morning with or without food to assess tolerance. If well tolerated, you may increase to the full serving of 2 capsules as needed or as determined by your healthcare provider.
CAUTION: This product contains 150 mg of caffeine per serving, along with other stimulating ingredients. It is not intended for individuals sensitive to caffeine. Start with 1 capsule to assess tolerance. If well tolerated, you may increase to the recommended serving. Always consult your healthcare professional before use, especially if you have a medical condition or are taking medication. Do not use if you are pregnant or nursing. Keep out of reach of children.
Clinically-proven, powerhouse ingredients for game-changing benefits.
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Methylcobalamin (Vitamin B12)
Essential for mitochondrial energy metabolism
What is it? Vitamin B12 is a vital nutrient that supports energy production, neurotransmitter balance, and cognitive function. It plays a key role in dopamine and serotonin synthesis—essential for motivation, mood, and mental clarity—while also supporting red blood cell formation and mitochondrial energy metabolism. B12 helps maintain healthy homocysteine levels, reducing oxidative stress and promoting long-term brain health.
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Fermented Salidrosides
Supports mitochondrial function
What is it? Salidroside is a bioactive tyrosol glycoside found in Rhodiola rosea, an adaptogenic plant traditionally used to enhance endurance, mental clarity, and resilience to fatigue. Our formula features SalidroPure™, a highly purified form of salidroside produced through precision fermentation—providing a sustainable and stable alternative to wild-harvested rhodiola.
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Pyridoxal-5’-Phosphate (Vitamin B6)
Assists in neurotransmitter synthesis
What is it? Vitamin B6 is an essential nutrient that plays a key role in neurotransmitter synthesis, supporting the production of dopamine, serotonin, and GABA—critical for focus, mood, and mental clarity. In its active form, Pyridoxal-5'-Phosphate (P5P), B6 helps regulate homocysteine levels, which is important for brain health and cognitive function.
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Dynamine® (Methylliberine)
Enhances energy
What is it? Methylliberine (Dynamine®) is a naturally occurring alkaloid found in kucha tea (Camellia assamica var. kucha) that shares structural similarities with caffeine and theacrine. Traditionally consumed in tea, methylliberine has been recognized for its potential to enhance energy, mood, and focus without the jitters or crash associated with stimulants. -
TeaCrine® Theacrine
Supports focus
What is it? TeaCrine® (Theacrine) is a naturally occurring purine alkaloid found in kucha tea (Camellia assamica var. kucha) that supports energy, focus, and mood without the jitters or crash associated with caffeine. Traditionally consumed for its invigorating effects, theacrine has been recognized for promoting mental clarity and endurance.
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N-Acetyl-L-Tyrosine
Supports mental resilience
What is it? N-Acetyl L-Tyrosine (NALT) is a bioavailable form of L-tyrosine, a key precursor to dopamine, the neurotransmitter involved in motivation, focus, and cognitive flexibility. Found naturally in protein-rich foods, tyrosine plays a crucial role in supporting mental resilience, especially under stress or fatigue. -
Camellia sinensis (L-Theanine)
Reduces jitters
What is it? L-Theanine is a naturally occurring amino acid found in tea leaves, known for its ability to promote relaxation without sedation. It works by promoting alpha brain wave activity, a pattern associated with calm focus and mental clarity.
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Caffeine Anhydrous
Promotes focus and energy
What is it? Caffeine is a naturally occurring stimulant found in coffee, tea, and other plant sources, known for its ability to enhance alertness and mental energy. It works by blocking adenosine, a neurotransmitter that promotes relaxation, leading to increased wakefulness and focus.
Motivation has helped hundreds of thousands of customers focus—and follow through.
Don't just take our word for it. See for yourself what Thesis customers experience within 60 days of taking Motivaton.
*These claims are based on a previous version of the Motivation formula. The data comes from an open-label consumer perception survey conducted in September 2024, which included at least 79 customers who had been using that version for 60 days or more. Participants received a $10 rebate for sharing their feedback. The previous formula included Artichoke, Vitamin B12, Methylliberine, L-Phenylalanine, Forskolin, and optionally caffeine and L-theanine. The formula has since been updated. A new study evaluating the current formula is planned, and updated claims are expected by December 2025.
NO UNNECESSARY FILLERS
100% VEGAN
NON-GMO
GAME-CHANGING RESULTS
QUALITY GUARANTEED
THIRD-PARTY TESTED
NO UNNECESSARY FILLERS
100% VEGAN
NON-GMO
GAME-CHANGING RESULTS
QUALITY GUARANTEED
THIRD-PARTY TESTED
Find more clarity, motivation, and stability over time.
Ignite your energy and drive
Caffeine, Dynamine®, and B6 may quickly boost dopamine and focus—helping you feel energized and clear-headed.*
More momentum, less procrastination
NALT, SalidroPure™, and B vitamins help sustain dopamine and reduce fatigue, so it’s easier to take action.*
Stay motivated under pressure
TeaCrine®, Dynamine®, and B vitamins support focus and steady energy—helping you stay driven without burnout.*
Sustain motivation for the long haul
With ingredients like B6, SalidroPure™, and NALT, you may begin reinforcing motivation pathways for lasting drive, clarity, and resilience.*
Collapsible content
Passed Microbial Testing
Passed Microbial Testing
We analyze all of our formulas for microorganisms including bacteria, viruses, and fungi.
Passed Active Ingredients
Passed Active Ingredients
We verify that every formula contains the exact amounts of active ingredients listed on the label.
Passed Heavy Metal Testing
Passed Heavy Metal Testing
We screen each batch for harmful heavy metals like lead, arsenic, cadmium, and mercury.
Passed Pesticide Testing
Passed Pesticide Testing
We test raw materials to ensure they’re free from pesticide residues, even trace amounts.
Nootropics needed pharmaceutical-grade testing. We delivered.
Nootropics needed pharmaceutical-grade testing. We delivered.
Rigorous testing and comprehensive consumer trials come standard for pharmaceutical drugs, but not nootropics. We weren’t satisfied with existing scientific data around active ingredients, so when we founded Thesis, we started to collect our own.
Today, we’ve conducted thousands of trials, and collected data from 7.3 million customers and counting. Our 5-part formulation process builds from all of this so you can trust that when you choose Thesis, you’re not guessing with nootropics. You’re choosing a cognitive conditioner that'll actually work.
Clinically researched. Precisely formulated.
Clinically researched. Precisely formulated.
Thesis uses isolated, plant-derived compounds rather than blends or extractions. This allows us to control consistency and experiment to determine the most effective dose of each ingredient to get the best results possible.
Many nootropics make baseless claims. We conduct real-world testing.
Many nootropics make baseless claims. We conduct real-world testing.
We conduct continuous beta testing and open-label trials to assess real-world effectiveness. Our studies are designed with the rigor and ethical standards typically reserved for pharmaceutical clinical trials.
Thesis has run over 30 beta tests
with real customers.
Thesis reads and analyzes 700+
studies when formulating.
Thesis products have been evaluated by 7.3 million customers.
An informed hypothesis
An informed hypothesis
Thesis’ science team and board of scientific advisors are constantly iterating based on our own data, new studies and cognitive research. Every process begins with a systematic review of literature that helps inform a hypothesis we set out to validate at scale. We then formulate based on these hypotheses.
Blind trials.
Blind trials.
With formulas in hand, we conduct a series of two week long blind trials. Hundreds of participants receive our formulas and a questionnaire based on a set of scientific criteria designed to standardize the results.
Analyze and iterate.
Analyze and iterate.
At the end of a trial all data is analyzed to determine the most effective formulation and that formula is rolled at a larger scale, evaluated again and improved if necessary. Product development is a continuous process at Thesis, we’re always iterating, testing and improving.
We’re devoted to continual improvement.
We’re devoted to continual improvement.
Our process is driven by two questions: why and how. We’re constantly reevaluating every decision we’ve made, and asking new questions in search of better outcomes for those who love and trust Thesis.
Here are the latest questions that drive what we do:
Which ingredient combinations most effectively support distraction-proof focus in a dopamine-saturated world?
Modern life hijacks attention with constant pings, scrolls, and dopamine spikes. Clarity targets this head-on by combining Citicoline, Lion’s Mane, and 7,8-DHF to promote neuroplasticity, acetylcholine signaling, and dopamine regulation. This stack helps support distraction resistance, sustained attention, and the deep work required for modern cognitive demands.
How can we support our brains to thrive now and stay sharp for decades to come?
Cognitive health isn’t just about a better workday. It’s about protecting what makes you you. From dopamine and Acetylcholine for daily drive and focus, to Sulforaphane, Spermidine, and mitochondrial activators for long-term resilience, our formulas are designed to support both high performance today and brain longevity tomorrow.
How does Stress Reset better support serum cortisol levels compared to previous formulations?
Stress Reset combines Shoden® Ashwagandha, clinically shown to reduce cortisol by up to 67% and occasional anxiety by 59%, with Zembrin® and Salidrosides for sharper mood regulation and cognitive flexibility. This version supports serotonin, dopamine, and alpha wave activity, without sedation or crash.
Reviews
FAQ'S
What are nootropics, and how do they work?
What are nootropics, and how do they work?
Nootropics are supplements that support cognitive health. They've been shown to boost motivation and focus, spark creativity, maintain long-term memory, balance mood, and more.
These potent ingredients—found in nature—help support cognition. Some nootropics, like Ashwagandha and Lion’s Mane, have been used for thousands of years. Others, like caffeine, may already be part of your daily routine.
Nootropics work by increasing brain activity by delivering more oxygen and nutrients to the brain, helping brain cells communicate better and increasing neuroplasticity–how adaptable your brain is to learning and experiencing.
Consistent, long-term nootropic use fosters healthy neuron growth, improving overall brain health and function, and supporting memory, focus, and overall mental performance.
Where can I find more information on each ingredient?
Where can I find more information on each ingredient?
If you want to learn more about the science behind each ingredient, check out the Ingredients page on our website.
To discuss the function or science behind our ingredients, speak with our Customer Care Team at 646-647-3599 or email us at hello@takethesis.com.
What’s unique about Thesis nootropics?
What’s unique about Thesis nootropics?
Instead of a one-size-fits-all approach, Thesis offers unique formulas made with clinically studied ingredients that complement one another to target different cognitive goals. Whether you’re looking to sharpen your working memory, boost mental clarity, or stay calm under pressure, there’s a formula to meet you where you are.
Can I open the capsules and pour them into water?
Can I open the capsules and pour them into water?
You can — but we don’t recommend it. We encapsulate the ingredients because they have a strong, unpleasant taste. If you have a hard time swallowing capsules, it is perfectly safe to mix the contents into a smoothie, juice, or flavored drink to help mask the taste.
What are the long-term effects?
What are the long-term effects?
In clinical trials, none of our ingredients show negative long-term effects. Many nootropics become more effective over time due to the compounding effects on brain health and the structural integrity of neurons.
Early research studying the long-term effects of certain nootropics ingredients shows improvement in cognitive traits like memory retention, cognitive flexibility, and focus following persistent use.
What is a daily dose?
What is a daily dose?
A daily dose is a single packet, containing two or three brown capsules and one white capsule that contains caffeine. If you ordered a caffeine-free version, your packet will only contain the brown capsules. There are six packets in each box of your formula, e.g., Energy, Clarity, Motivation are all “formulas”. Most people take one packet per day, containing all of the capsules enclosed.
Does recommended dosage vary by individual factors like weight?
Does recommended dosage vary by individual factors like weight?
We standardize our doses across our different ingredient blends based on clinically studied dosages. However, individual factors like weight, metabolism, and tolerance can sometimes impact effectiveness.
If you want guidance on how to change the dose to reach the desired effects, give us a call so we can help adjust.
It’s important to speak with your primary medical provider before starting any new supplement or altering any course of medication.
Can I take more than one formula per day?
Can I take more than one formula per day?
Thesis was designed to be taken once daily. However, we understand that your needs may vary. You can safely take up to two formulas (e.g., Energy and Creativity) in a given day if you prefer.
We recommend spacing each formula by at least 4 hours to avoid any potential interactions or absorption issues. For guidance on combining formulas safely and effectively, speak with our Customer Care Team who can tailor recommendations to your specific needs and goals. Additionally, we always recommend speaking with your healthcare provider before starting a new supplement routine.
Will I become reliant on taking my formula?
Will I become reliant on taking my formula?
No, you won’t develop a dependency on any of our formulas. Because nootropics are non-habit-forming compounds, you have the flexibility to pause or stop taking them without experiencing unwanted side effects.
Can I take Thesis if I’m under 18?
Can I take Thesis if I’m under 18?
Our product is one of the most comprehensive nootropics systems on the market and our ingredients are backed by hundreds of clinical research papers.
Unfortunately, the research conducted on these ingredients did not include participants who were under the age of 18. We advise against children taking our product and encourage you to consult a pediatric healthcare provider for advice tailored to minors.
Is it safe to take if I’m pregnant or breastfeeding?
Is it safe to take if I’m pregnant or breastfeeding?
Our product is one of the most comprehensive nootropics systems on the market and our ingredients are backed by hundreds of clinical research papers.
Unfortunately, the research conducted on these ingredients did not include participants who were pregnant, nursing, or breastfeeding. For that reason, you should always consult your healthcare provider before starting any new supplement to ensure it is safe for you and your baby.
Are there any known side effects?
Are there any known side effects?
Everybody responds to supplements differently. Side effects are rare but possible, especially when introducing new supplements to your routine. They can include a mild upset stomach or mild headache, and are often remedied by taking your formula with food instead of on an empty stomach.
